Saviour or punisher? Tadalafil is a prescription medicine used primarily to treat erectile dysfunction.
What does Tadalafil do?
Tadalafil targets an enzyme called phosphodiesterase-5 (PDE-5) which inhibits a chemical called cyclic guanosine monophosphate (cGMP). During sexual stimulation, cGMP is produced to cause the blood vessels in the penis to dilate, giving rise to an erection. PDE-5 is found in high levels in the lungs, retina and of course, the penis. It must be noted that whilst tadalafil will assist with the blood flow to the penis, it will not generate the erection automatically.
As a treatment for benign prostatic hyperplasia, taking tadalafil will help to relax the muscles in the prostate and the bladder. This should help relieve the symptoms of BPH which include difficulty to commence urinating, a disrupted urine flow and possibly the need to strain or push in order to continue.
Pulmonary arterial hypertension, although rare, is a serious form of high blood pressure. The blood vessels connecting the heart and the lungs become constricted, forcing the heart to work harder to supply adequate blood. Tadalafil works to alleviate the constriction, relaxing the blood vessels. It will allow breathing to require far less effort and will also assist with exercise.
Tadalafil in the Media
Illegal Energy Candy (Feb 2020)
There have been reports of a type of candy being sold in Malaysian convenience stores with trace elements of tadalafil. Tadalafil is a prescription drug and therefore not a legal ingredient of a food source, especially one marketed for children. The manufacturers were naturally omitting this information from their packaging, leaving retailers unaware of the potential dangers of consuming the product
Mass Product Recall (Apr 2019)
Health Canada sent out a warning about 23 products which may include dangerous and unlabelled ingredients, tadalafil being one of them. The majority of these products are marketed as sexual enhancers. In each of these cases, approval by Health Canada had not been given, meaning they had not been assessed for safety, quality or effectiveness.
Tadalafil Research Studies
This extensive study tested tadalafil across a wide demographic of people from previous studies in relation to erectile dysfunction. Common findings were for tadalafil users experiencing more reliable erections and achieving successful sexual intercourse with their partners than the placebo controlled individuals.
Combatting the Enlarged Prostate
A combined research team from Nashville, Dallas, Indianapolis and San Antonia were testing men with benign prostatic hyperplasia for improvements to their lower urinary tract symptoms. 200 men aged over 40 were analysed with one group given a placebo and the other 20mg of tadalafil.
This study of pulmonary arterial hypertension focussed on 18 younger people (aged 4-24) treated with an alternate PDE-5 inhibitor. Tadalafil was installed as the new treatment and after 6 weeks there was a noted improvement in the severity of the patient’s symptoms. With no apparent side effects, the researchers concluded that tadalafil was a suitable alternative treatment to PAH.
Tadalafil Anecdotal Claims
As you can well imgaine, tadalafil can potentially restore and reinvigorate the sex lives of plenty of frustrated people and their partners. This first review needs to be quoted in full. Top marks for creativity.
User ComeFromBehindVictory states “From Zero to Hero. My newly reinvigorated wife calls Cialis (tadalafil) “the 8th Wonder of the World!” So, from the Struggle to the Reckoning and everything in between: from Bored, Deplored and Ignored to Lord of the Sword Restored now Adored. She’s Floored. I Scored. Hard to Afford yet Cialis wins, Top Shelf Award.”
Others were also glowing in their praise
Dates: 27/01/20; 21/01/20
CryNoMo reported that tadalafil works swiftly and lasts for longer than viagra. They also said the body returned to normal naturally without drugs.
Mikexray had been taking tadalafil for benign prostatic hyperplasia. He states that it has aided him with his urges to urinate, improved his sleep and empties his bladder with ease. He hasn’t recorded any negative side effects and has vastly improved his quality of life.
Legal Status in Australia
Tadalafil has been approved as a prescription medicine by the Therapeutic Goods Administration department of the Australian Government.
Where to buy Tadalafil
Tadalafil can be purchased from different online retailers.
PerthMeds.com is offering tadalafil as Cialis in various quantities and concentrations. They are also offering discounts on some secondary purchases.
okdrugstore.com is also selling Cialis in concentrations ranging from 2.5mg to 20mg in various quantities.
Tadalafil Dosage and Usage
A standard prescription of tadalafil is 5mg per day. Depending on the clinical case and severity of symptoms, 10mg or 20mg daily dosages are not uncommon. Doubling a dose to try and cover for a missed one is ill advised. One pill per day of tadalafil is all that is recommended.
For erectile dysfunction, the tablet should be taken at least half an hour before any anticipated sexual activity. Doses should be taken at approximately the same time each day to maintain levels.